|Year : 2022 | Volume
| Issue : 1 | Page : 23-26
Symptom manifestation of dental local anesthesia with patients who recently received COVID-19 vaccine
Ahmed Abdullah Alaskari1, Ebtihal Saad Almutairi2, Demah Saleh Midshil Alharthi1, Deena Ali Obaid Alqahtani1, Atheer Ali Mueedh Alhassan1, Roula S Albounni3
1 College of Dentistry, King Khalid University, ABHA, Kingdom of Saudi Arabia
2 College of Dentistry, King Saud University, Riyadh, Kingdom of Saudi Arabia
3 Department of Restorative and Endodontic, Riyadh Elm University, Riyadh, Kingdom of Saudi Arabia
|Date of Submission||20-Sep-2021|
|Date of Acceptance||09-Oct-2021|
|Date of Web Publication||29-Apr-2022|
Prof. Roula S Albounni
Department of Restorative and Endodontic, Riyadh Elm University, PO Box 8489, Riyadh 12734
Kingdom of Saudi Arabia
Source of Support: None, Conflict of Interest: None
Introduction: As a result of Coronavirus Disease (COVID-19) pandemic. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) caused the severe viral pneumonia . Countries have been applying test regulations, vaccination is the top strategy to combat it.
Aim: To determine if there was any negative impact of dental local anesthesia on the vital medical condition of patients who recently received the Covid-19 vaccine.
Materials and Methods: Before participating in the study, patients had to read and sign a consent form. The following treatments were performed under local anesthesia: ten definitive restorations; two tooth extractions; two scalings and prophylaxis; three root planning; and one root canal treatment. Lidocaine with epinephrine was used on three patients, lidocaine without epinephrine on one patient, and scandicaine2% (mepivacaine hydrochloride) on 13 patients. A questionnaire containing nine specific questions was developed for this study, beginning with a patient's personal information. In the second group, we asked about the symptoms after getting the covid 19 vaccine, and in the third group, we asked about the symptoms after dental work.
Results and Discussion: With the limitation of this study, it was evident that there was no correlation between vaccination against Covid-19 and local anesthesia in dental treatment with healthy patients. As the Local anesthetics produce anesthesia by inhibiting nerve ending excitation or by blocking the conduction of peripheral nerves. And COVID-19 vaccine works on the body's immune system. Statistical significance was established at P ≤ 0.05.
Conclusion: According to this study, there was no correlation between vaccination against Covid-19 and local anesthesia in dental treatment with healthy patients.
Keywords: COVID-19, dental local anesthesia, vaccine
|How to cite this article:|
Alaskari AA, Almutairi ES, Alharthi DS, Alqahtani DA, Alhassan AA, Albounni RS. Symptom manifestation of dental local anesthesia with patients who recently received COVID-19 vaccine. Saudi J Oral Sci 2022;9:23-6
|How to cite this URL:|
Alaskari AA, Almutairi ES, Alharthi DS, Alqahtani DA, Alhassan AA, Albounni RS. Symptom manifestation of dental local anesthesia with patients who recently received COVID-19 vaccine. Saudi J Oral Sci [serial online] 2022 [cited 2022 Dec 5];9:23-6. Available from: https://www.saudijos.org/text.asp?2022/9/1/23/344401
| Introduction|| |
Globally, health-care systems faced unprecedented challenges as a result of coronavirus disease 2019 (COVID-19). Severe viral pneumonia that began in Wuhan, China, in December 2019 was caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2); as of June 29, 2021, the virus had infected 182 million people and killed 3.9 million. Since the pandemic was declared, countries have implemented test regulations, contact tracing, travel bans, and lockdowns; vaccination is the main means of preventing it. Today, many vaccines are available to minimize the spread of COVID-19. Since the onset of the COVID-19 pandemic, many concerns have been raised in regards to the safe anesthesia management of patients suffering from this disease. For patients with COVID-19, regional anesthesia, whether peripheral nerve or neuraxial, is a safe alternative. Methods that minimize pulmonary function involvement should be considered. Local anesthetics are used in dental procedures to achieve a loss of perception and analgesia (loss of pain sensation), as well as paralysis (loss of muscle control).
The most important question is, “Does local anesthesia used for dental treatment have an adverse effect on patients after taking the COVID-19 vaccine?”
Aim and objective
This study aimed at investigating the possible negative effects of dental local anesthesia on the vital medical condition of the patient who recently received the COVID-19 vaccine.
A recent COVID-19 vaccination does not result in any symptoms following the administration of local anesthetic.
| Materials and Methods|| |
In this study, 17 patients were randomly selected to participate.
The patients required to be included were as follows:they were adults (over 18 years old), they received the COVID-19 vaccine within 7 days (16 received the Biontech vaccine, one received the AstraZeneca vaccine [Table 2]). Further, they required dental treatment (simple restoration, simple extraction, or scaling) after vaccination [Table 3].
Exclusion criteria included patients with systemic chronic diseases, special medical conditions, severe reactions to vaccinations, disorder psychological conditions, and individuals with special physiological conditions such as pregnant women and nursing mothers.
Research Center at REU was reviewed and approved by the Institutional Review Board.
Before participating in the study, patients had to read and sign a consent form.
The following treatments were performed under local anesthesia: ten definitive restorations; two tooth extractions; two scaling and prophylaxis; three root planning and one root canal treatment .
Lidocaine with epinephrine was used on three patients, lidocaine without epinephrine on one patient, and Scandicaine 2% (mepivacaine hydrochloride) on 13 patients. [Table 1].
Dental treatment is provided at Riyadh Elm University Hospital, King Khalid University Hospital, and a few private dental clinics.
A questionnaire containing nine specific questions was developed for this study, beginning with a patient's personal information. In the second group, we asked about the symptoms after getting the COVID-19 vaccine, and in the third group, we asked about the symptoms after dental work.
Its primary objective was to determine whether local dental anesthesia could adversely affect a patient's vital medical condition after receiving the COVID-19 vaccine. The questionnaire was to be filled out after 2 days by the patients.
This form was given to patients to fill out and return 2 days after their dental procedure. https://forms.gle/EHpyMVF2PdtCed5z5.
Subsequently, all data were collected and subjected to statistical analysis [Table 4].
| Results|| |
Descriptive statistics of frequency distribution and percentages were calculated.
| Discussion|| |
It has recently been suggested that local anesthetic dental treatment should be avoided in the first few days after vaccination.
On the basis of clinical trials conducted in this study, we can state that local anesthesia and COVID-19 vaccination have no relationship.
Local anesthetics cause anesthesia by inhibiting nerve-ending excitation or by blocking the conduction of peripheral nerves. Anesthetics accomplish this by binding to sodium channels and inactivating them reversibly. The COVID-19 vaccine stimulates the body's immune system. Pfizer-BioNTech COVID-19 vaccine contains an mRNA that encodes the virus' spike protein encapsulated in a lipid nanoparticle.
Upon injection, the cells release the spike protein, which triggers the immune system to recognize the virus. An AstraZeneca and University of Oxford vaccine uses a technology called Vaccitech. This virus uses a replication-deficient chimpanzee viral vector that is based on a weakened version of chimpanzee viruses known to cause colds (adenoviruses). The spike protein's genetic material is contained in it. As a result of vaccination, the cells produce the spike protein, which stimulates the immune system to attack the SARS-CoV-2 virus.
Data contributes to a better understanding of Lin et al., whose studies dealt with implications of anesthesia and vaccination, which showed that anesthesia and surgery affect the immune response, and complications associated with vaccination during the perioperative period are not fully understood.
We agree with Dr. Abd Al-Aly who stated that receiving local or general anesthesia for recently vaccinated patients has no adverse effects. Furthermore, Dr. Amin's previous research focused on COVID-19 vaccine and dental implants. These results demonstrate that Pfizer or Moderna vaccines should not have any effect on dental implants or bone grafting.
The results of this study cannot be generalized due to a small sample size of healthy adults (over 18 years old) and adults with medical conditions.
Further research is needed in patients with systemic chronic diseases, special medical conditions, severe symptoms after vaccination, and special physiological conditions such as pregnancy and breastfeeding.
| Conclusion|| |
According to this study, there was no correlation between vaccination against COVID-19 and local anesthesia in dental treatment with healthy patients.
Financial support and sponsorship
Conflicts of interest
There are no conflicts of interest.
| References|| |
Odeh ND, Babkair H, Abu-Hammad S, Borzangy S, Abu-Hammad A, Abu-Hammad O. COVID-19: Present and future challenges for dental practice. Int J Environ Res Public Health 2020;17:3151.
Stafie CS, Murariu AM. Local dental anesthesia: Patients at risk for anaphylaxis. Rom J Oral Rehabil 2020;12(4):190.
Lin C, Vazquez-Colon C, Geng-Ramos G, Challa C. Implications of anesthesia and vaccination. Paediatr Anaesth 2021;31:531-8.
[Table 1], [Table 2], [Table 3], [Table 4]